4-羟基丙泊酚-4-O-β-D-葡糖醛酸
异丙酚代谢产物
有货
基本信息
| 产品名称 | 4-羟基丙泊酚-4-O-β-D-葡糖醛酸 |
|---|---|
| 英文名称 | 4-Hydroxy Propofol 4-O-β-D-Glucuronide |
| 英文别名 | 4-Hydroxy-3,5-bis(1-methylethyl)phenyl β-D-Glucopyranosiduronic Acid |
| 运输条件 | 超低温冰袋运输 |
一般描述
4-羟基丙泊酚1-O-β-D-葡糖醛酸苷是丙泊酚的代谢产物，在4位被O-连接的β-糖苷键修饰。丙泊酚是一种酚衍生物，被认为可调节辣椒素对瞬时受体电位类香草素亚型1（TRPV1）受体的敏感性。TRPV1是一种辣椒素受体，主要作为感觉神经元中的非选择性阳离子通道，可特异性检测疼痛刺激，低pH值和高温。
4-Hydroxy Propofol 1-O-β-D-Glucuronide is a metabolite of Propofol modified at position 4 with an O-linked β-glycosidic bond. Propofol is a phenol derivative that is suggested to modulate the sensitivity of capsaicin to the transient receptor potential vanilloid subtype-1 (TRPV1) receptor. TRPV1 is a Capsaicin receptor that behaves as a non-selective cation channel that is mainly found in the sensory neurons, and specifically detects painful stimuli, low pH and heat.
相关属性
| CAS编号 | 115005-78-2 |
|---|---|
| 熔点 | 116-118° C |
| 溶解性 | Soluble in Methanol |
| 储存温度 | -20°C储存 |
| 密度 | 1.4 g/cm3(Predicted) |
| 分子量 | 370.39 |
| 分子式 | C18H26O8 |
| 品牌 | Jinpan |
| Smiles | CC(C)C1=CC(O[C@H]2OC([C@H](O)[C@@H](O)[C@H]2O)C(O)=O)=CC(C(C)C)=C1O |
| PubChem CID | 10384525 |