2-（4'-（二甲基氨基）苯基）-6-甲基-苯并噻唑

2-（4′-（（二甲基氨基）苯基）-6-甲基-苯并噻唑是硫黄素-T的不带电荷衍生物，其亲和力比硫黄素-T高6倍，并且对淀粉样沉积物显示出高亲和力[Ki = 143 nM。 Ab（1-40）]。它可以穿过血脑屏障，并在验尸后的阿尔茨海默氏病脑中染色斑块和神经原纤维缠结。

2-(4′-(dimethylamino)phenyl)-6-methyl-benzothiazole is an uncharged derivative of Thioflavin-T, displaying 6-fold higher affinity than Thioflavin-T, and shows high affinity for amyloid deposits [Ki = 143 nM for Ab(1-40)]. It can cross the blood brain barrier, and stains both plaques and neurofibrillary tangles in post mortem Alzheimer’s disease brain.