肝素钠
185 USP units/mg
有货
基本信息
产品名称 | 肝素钠 |
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英文名称 | Heparin sodium salt |
别名 | 肝素钠盐 |
英文别名 | Sodium heparin;Sodium heparinate;Heparin sodium;Deligoparin sodium; Minolteparin sodium; Nadroparine sodium |
应用 | 生化研究,防止凝血酶原转变成凝血酶。 · Heparin sodium salt from porcine intestinal mucosa has been used in sLRP (soluble circulating low density lipoprotein receptor-related protein-1) purification from human plasma. · It has been used as a supplement in M199 medium for culturing of human umbilical vein endothelial cells. · It has been used as an anticoagulant agent during isolation of blood. |
规格或纯度 | 185 USP units/mg |
运输条件 | 冰袋运输 |
生化机理 | Heparin, Sodium salt is a low molecular weight heparin (LMWH) polymer that produces its major anticoagulant effect by activating antithrombin. This activation causes a conformational change in ATIII and allows for increased flexibility in its reactive site loop. Heparin is a highly sulfated glycosaminoglycan known for preventing clots. Heparin, Sodium Salt is also an activator of RyR and ATIII. |
一般描述
几乎无臭。无味。为一种天然多糖,取自猪或牛肠粘液或牛肺。有吸湿性。易溶于水(1g溶于20ml水),溶于盐水溶液,几乎不溶于乙醇、乙醚、丙酮、氯仿和苯。1%的水溶液pH为6.0-7.5。半数致死量(大鼠,静脉)354mg/kg。 生化研究,防止凝血酶原转变成凝血酶。
Heparin is mainly responsible for the delay in the coagulation of blood. It enhances the antithrombin-mediated inactivation of proteases in the coagulation pathway.
A heparin polymer that produces its anticoagulant effect by activating ATIII (antithrombin).
相关属性
CAS编号 | 9041-08-1 |
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敏感性 | 对湿度敏感 |
溶解性 | Soluble in water (100 mg/ml), DMSO (< 1 mg/ml), and ethanol (< 1 mg/ml). |
储存温度 | 2-8°C储存,充氩 |
RTECS | MI0850000 |
MDL号 | MFCD00081689 |
分子式 | |
品牌 | Jinpan |