PtdIns-（4,5）-P2（1,2-二棕榈酰）（钠盐）

磷脂酰肌醇（PtdIns）磷酸酯占总膜磷脂的一小部分，但它们在细胞信号的产生和传递中起着至关重要的作用。PtdIns-（4,5）-P2（1,2-二棕榈酰）是天然PtdIns的合成类似物，其在sn-1和sn-2位置包含饱和C16：0脂肪酸。该化合物包含与天然化合物相同的肌醇和二酰基甘油（DAG）立体化学。天然化合物是作用于PtdIns-（4）-P1的PtdIns-4-磷酸5-激酶的产物。磷酸肌醇（PI）特异性磷脂酶C水解PtdIns-（4,5）-P2生成肌醇三磷酸酯（IP3）和DAG，这是复杂的生化信号转导

The phosphatidylinositol (PtdIns) phosphates represent a small percentage of total membrane phospholipids, but they play a crucial role in the generation and transmission of cellular signals. PtdIns-(4,5)-P2 (1,2-dipalmitoyl) is a synthetic analog of natural PtdIns containing saturated C16:0 fatty acids at sn-1 and sn-2 positions. The compound contains the same inositol and diacylglycerol (DAG) stereochemistry as that of the natural compound. The natural compound is the product of PtdIns-4-phosphate 5-kinase acting on PtdIns-(4)-P1. Hydrolysis of PtdIns-(4,5)-P2 by phosphoinositide (PI)-specific phospholipase C generates inositol triphosphate (IP3) and DAG which are key second messengers in an intricate biochemical signal transduction cascade.