4-羟基丙泊酚-1-O-β-D-葡糖醛酸

4-羟基丙泊酚1-O-β-D-葡糖醛酸苷是通过快速清除丙泊酚的代谢产物，并通过尿苷二磷酸葡糖醛酸糖基转移酶进行葡糖醛酸化作用，后者也在第4位被羟基修饰。丙泊酚是一种酚衍生物，被认为可调节辣椒素对瞬时受体电位类香草素亚型1（TRPV1）受体的敏感性。TRPV1是一种辣椒素受体，主要作为感觉神经元中的非选择性阳离子通道，可特异性检测疼痛刺激，低pH值和高温。

4-Hydroxy Propofol 1-O-β-D-Glucuronide is a metabolite follwoing rapid clearance of Propofol linked with glucuronidation by the uridine diphosphate glucuronosyltransferases, which is also modified at position 4 with a hydroxy group. Propofol is a phenol derivative that is suggested to modulate the sensitivity of capsaicin to the transient receptor potential vanilloid subtype-1 (TRPV1) receptor. TRPV1 is a Capsaicin receptor that behaves as a non-selective cation channel that is mainly found in the sensory neurons, and specifically detects painful stimuli, low pH and heat.