钙黄绿素乙酰氧基甲酯
基本信息
产品名称 | 钙黄绿素乙酰氧基甲酯 |
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英文名称 | Calcein, AM |
别名 | 钙黄绿素乙酰氧基甲酯 |
英文别名 | Calcein, AM;Calcein O,O′-diacetate tetrakis(acetoxymethyl) ester;Calcein acetoxymethyl ester;CAL-AM |
规格或纯度 | ≥96.0% (HPLC),用于荧光分析 |
运输条件 | 超低温冰袋运输 |
一般描述
Calcein-AM is a hydrophobic non-fluorescent probe that can permeate the plasma membrane and can be hydrolyzed to Calcein , which is an extremely fluorescent and negatively charged molecule. The probe can be used to stain living cells and has been observed to fluoresce bright green in cytoplasmic Schwann cells. Calcein-AM has been reported to be a neutral substrate for Mdr (P-glycoprotein (Pgp) and multidrμg resistance protein (MRP)) and has been used in flow cytometry studies to analyze the function of P-gp and MRP. Studies sμggest that Calcein-AM can be used to detect MDR mediated resistance and to be transported by PGP from the plasma membrane. Mitochondrial permeability research has utilized Calcein as a cytosolic fluorophore. Has been used as a cytosolic fluorophore in mitochondrial permeability studies to image pore transition.A non-fluorescent, membrane permeable probe that can be hydrolyzed to a fluorescent molecule
Calcein-AM is a hydrophobic non-fluorescent probe that can permeate the plasma membrane and can be hydrolyzed to Calcein , which is an extremely fluorescent and negatively charged molecule. The probe can be used to stain living cells and has been observed to fluoresce bright green in cytoplasmic Schwann cells. Calcein-AM has been reported to be a neutral substrate for Mdr (P-glycoprotein (Pgp) and multidrug resistance protein (MRP)) and has been used in flow cytometry studies to analyze the function of P-gp and MRP. Studies suggest that Calcein-AM can be used to detect MDR mediated resistance and to be transported by PGP from the plasma membrane. Mitochondrial permeability research has utilized Calcein as a cytosolic fluorophore. Has been used as a cytosolic fluorophore in mitochondrial permeability studies to image pore transition.
A non-fluorescent, membrane permeable probe that can be hydrolyzed to a fluorescent molecule
相关属性
CAS编号 | 148504-34-1 |
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敏感性 | 对光敏感;湿度敏感 |
储存温度 | -20°C储存,充氩 |
MDL号 | MFCD05861516 |
分子量 | 994.87 |
分子式 | C46H46N2O23 |
EC号 | 200-664-3 |
品牌 | Jinpan |
备注 | 如果有可能,您尽量在同一天配置溶液,并在当天使用完它。但是,如果您需要预先配制储备溶液,我们建议您将溶液等份保存在-20°C的密封小瓶中。通常,它们最多可以使用一个月。在使用前和打开样品瓶之前,我们建议您让您的产品在室温下平衡至少1小时。有关AM酯的更多信息,请访问我们的AM酯常见问题页。需要更多关于溶解度,用法和处理的建议吗?请访问我们的常见问题(FAQ)页面以获取更多详细信息。 |
PubChem CID | 254767102 |