氯(2,2′:6′,2″-三联吡啶)铂(II)氯化二水合物
基本信息
| 产品名称 | 氯(2,2′:6′,2″-三联吡啶)铂(II)氯化二水合物 |
|---|---|
| 英文名称 | Chloro(2,2′:6′,2″-terpyridine)platinum(II) chloride dihydrate |
| 英文别名 | Dichloro(2,2′:6′,2′′-terpyridine)platinum(II) dihydrate |
| 规格或纯度 | ≥98% |
| 运输条件 | 常规运输 |
一般描述
氯(2,2′:6′,2″-三联吡啶)铂(II)氯化二水合物，也被鉴定为[（terpyr）PtCl] Cl，是Pt与叔吡啶配体和DNA嵌入剂的复合物。游离的[（terpyr）PtCl] Cl化合物的特征性UV-Vis谱带在加入ct-DNA后被修饰，从而可以对该相互作用进行光谱研究。[（terpyr）PtCl] Cl被证明可阻止pHV14质粒超螺旋形式在凝胶电泳中的迁移，并竞争性地抑制溴化乙锭染料的嵌入核酸结合。
Chloro(2,2′:6′,2″-terpyridine)platinum(II) chloride dihydrate, also identified as [(terpyr)PtCl]Cl, is a complex of Pt and a terpyridine ligand and a DNA intercalating agent. The characteristic UV-Vis bands of the free [(terpyr)PtCl]Cl compound are modified upon addition to ct-DNA, allowing spectroscopic investigation of this interaction. [(terpyr)PtCl]Cl is demonstrated to retard the mobility of the supercoiled form of pHV14 plasmid in gel electrophoresis and to competitively inhibit the intercalative nucleic acid binding of the Ethidium bromide dye.
相关属性
| CAS编号 | 151120-25-1 |
|---|---|
| 储存温度 | 室温,干燥 |
| 分子量 | 535.28 |
| 分子式 | C₁₅H₁₁Cl₂N₃Pt・2H₂O |
| 品牌 | Jinpan |
| Smiles | C1=CC=NC(=C1)C2=NC(=CC=C2)C3=CC=CC=N3.O.O.Cl[Pt]Cl |
| PubChem CID | 16211752 |