4-O-（α-D-半乳糖吡喃糖基）-D-半乳糖
基本信息
| 产品名称 |
4-O-（α-D-半乳糖吡喃糖基）-D-半乳糖 |
| 英文名称 |
4-O-(α-D-Galactopyranosyl)-D-galactose |
| 英文别名 |
(2R,3R,4S,5R,6R)-2-(hydroxymethyl)-6-[(2R,3R,4R,5R)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxane-3,4,5-triol |
| 运输条件 |
超低温冰袋运输 |
一般描述
4-O-（α-D-半乳糖吡喃糖基）-D-半乳糖是与尿毒症受体结合的特异性配体。大肠杆菌和痢疾志贺氏菌毒素。另外，4-O-（α-D-半乳糖吡喃糖基）-D-半乳糖定义了P血型系统。这些研究是用| E进行的。表达I类和II类PapG粘附素的大肠杆菌表明4-O-（α-D-半乳糖吡喃糖基）-D-半乳糖抑制人红细胞的血凝。此外，当在O-1和O-3’位置的芳环上存在取代时，更有效地影响I类粘附素。
4-O-(α-D-Galactopyranosyl)-D-galactose is a specific ligand that binds to receptors of uropathogenic|E. coli|and|Shigella dysenteriae|toxin. In addition, 4-O-(α-D-Galactopyranosyl)-D-galactose defines the P blood group system. These studies conducted with|E. coli|that express class I and class II PapG adhesins indicate that 4-O-(α-D-Galactopyranosyl)-D-galactose inhibits hemagglutination of human erythrocytes. Furthermore, the class I adhesins are more potently effected when there is a substitution on the aromatic ring at the O-1 and the O-3′ positions.
相关属性
| CAS编号 |
80446-85-1 |
| 折光率 |
n20D1.65 (Predicted) |
| 熔点 |
77-80° C |
| 沸点 |
~ 667.9° C at 760 mmHg (Predicted) |
| pKa值 |
pKₐ: 12.02 (Predicted) |
| 溶解性 |
Soluble in water, and methanol. |
| 储存温度 |
-20°C储存 |
| 密度 |
~1.8 g/cm3(Predicted) |
| 分子量 |
342.34 |
| 分子式 |
C₁₂H₂₂O₁₁ |
| 品牌 |
Jinpan |
| Smiles |
C([C@@H]1[C@@H]([C@@H]([C@H]([C@H](O1)O[C@H]2[C@H](OC([C@@H]([C@H]2O)O)O)CO)O)O)O)O |
| IC50 |
Inhibition of Cryptosporidium parvum recombinant Galactose/N-acetylgalactosamine-specifIC₅₀ectin binding to Caco2A cells: IC₅₀= 2.5 mM |
| PubChem CID |
44560080 |
