氯(2,2′:6′,2″-三联吡啶)铂(II)氯化二水合物
基本信息
产品名称 |
氯(2,2′:6′,2″-三联吡啶)铂(II)氯化二水合物 |
英文名称 |
Chloro(2,2′:6′,2″-terpyridine)platinum(II) chloride dihydrate |
英文别名 |
Dichloro(2,2′:6′,2′′-terpyridine)platinum(II) dihydrate |
规格或纯度 |
≥98% |
运输条件 |
常规运输 |
一般描述
氯(2,2′:6′,2″-三联吡啶)铂(II)氯化二水合物,也被鉴定为[(terpyr)PtCl] Cl,是Pt与叔吡啶配体和DNA嵌入剂的复合物。游离的[(terpyr)PtCl] Cl化合物的特征性UV-Vis谱带在加入ct-DNA后被修饰,从而可以对该相互作用进行光谱研究。[(terpyr)PtCl] Cl被证明可阻止pHV14质粒超螺旋形式在凝胶电泳中的迁移,并竞争性地抑制溴化乙锭染料的嵌入核酸结合。
Chloro(2,2′:6′,2″-terpyridine)platinum(II) chloride dihydrate, also identified as [(terpyr)PtCl]Cl, is a complex of Pt and a terpyridine ligand and a DNA intercalating agent. The characteristic UV-Vis bands of the free [(terpyr)PtCl]Cl compound are modified upon addition to ct-DNA, allowing spectroscopic investigation of this interaction. [(terpyr)PtCl]Cl is demonstrated to retard the mobility of the supercoiled form of pHV14 plasmid in gel electrophoresis and to competitively inhibit the intercalative nucleic acid binding of the Ethidium bromide dye.
相关属性
CAS编号 |
151120-25-1 |
储存温度 |
室温,干燥 |
分子量 |
535.28 |
分子式 |
C₁₅H₁₁Cl₂N₃Pt・2H₂O |
品牌 |
Jinpan |
Smiles |
C1=CC=NC(=C1)C2=NC(=CC=C2)C3=CC=CC=N3.O.O.Cl[Pt]Cl |
PubChem CID |
16211752 |