Anti-Human CD230 (PrP) PE

货　　号：12-9230-42

产品规格：100 tests

原  产  地：USA

参考价格：2988 （参考价格，以实际价格为准）

优惠价格：

Anti-Human CD230 (PrP) PE   12-9230-42

   
Anti-Human CD230 (PrP) PE
Also known as: Prion protein
Clone: 4D5
RUO: For Research Use Only. Not for use in diagnostic procedures.

Host     Mouse
Isotype     IgG1, kappa
Reactivity     Human
Conjugate     PE
Laser     Blue Laser, Green Laser, Yellow-Green Laser
Excite     488 – 561 nm
Reported Applications     Flow Cytometric Analysis

References: Durig J, Giese A, Schulz-Schaeffer W, Rosenthal C, Schmucker U, Bieschke J, Duhrsen U, Kretzschmar HA. Differential constitutive and activation-dependent expression of prion protein in human peripheral blood leucocytes. Br J Haematol. 2000 Mar;108(3):488-95. (PubMed)

Barclay GR, Hope J, Birkett CR, Turner ML. Distribution of cell-associated prion protein in normal adult blood determined by flow cytometry. Br J Haematol. 1999 Dec;107(4):804-14. (PubMed)

Holada K, Simak J, Risitano AM, Maciejewski J, Young NS, Vostal JG. Activated platelets of patients with paroxysmal nocturnal hemoglobinuria express cellular prion protein. Blood. 2002 Jul 1;100(1):341-3. (PubMed)

Anti-Human CD267 (TACI) PE

货　　号：12-9217-41

产品规格：25 tests

原  产  地：USA

参考价格：1788 （参考价格，以实际价格为准）

优惠价格：

Anti-Human CD267 (TACI) PE  12-9217-41

Also known as: TNFRSF13B
Clone: 11H3
RUO: For Research Use Only. Not for use in diagnostic procedures.
Host     Mouse
Isotype     IgG2a
Reactivity     Human
Conjugate     PE
Laser     Blue Laser, Green Laser, Yellow-Green Laser
Emit     575 nm
Excite     488 – 561 nm
Reported Applications     Flow Cytometric Analysis

References: von Bulow GU, van Deursen JM, Bram RJ. Regulation of the T-independent humoral response by TACI.Immunity. 2001 May;14(5):573-82.

Ng LG, Sutherland AP, Newton R, Qian F, Cachero TG, Scott ML, Thompson JS, Wheway J, Chtanova T, Groom J, Sutton IJ, Xin C, Tangye SG, Kalled SL, Mackay F, Mackay CR. B cell-activating factor belonging to the TNF family (BAFF)-R is the principal BAFF receptor facilitating BAFF costimulation of circulating T and B cells.J Immunol. 2004 Jul 15;173(2):807-17.

Novak AJ, Darce JR, Arendt BK, Harder B, Henderson K, Kindsvogel W, Gross JA, Greipp PR, Jelinek DF. Expression of BCMA, TACI, and BAFF-R in multiple myeloma: a mechanism for growth and survival.Blood. 2004 Jan 15;103(2):689-94.

Sakurai D, Kanno Y, Hase H, Kojima H, Okumura K, Kobata T. TACI attenuates antibody production costimulated by BAFF-R and CD40. Eur J Immunol. 2007 Jan;37(1):110-8. PubMed

Sakurai D, Hase H, Kanno Y, Kojima H, Okumura K, Kobata T. TACI regulates IgA production by APRIL in collaboration with HSPG. Blood. 2007 Apr 1;109(7):2961-7. PubMed

Seshasayee D, Valdez P, Yan M, Dixit VM, Tumas D, Grewal IS. Loss of TACI causes fatal lymphoproliferation and autoimmunity, establishing TACI as an inhibitory BLyS receptor.Immunity. 2003 Feb;18(2):279-88.

Yan M, Wang H, Chan B, Roose-Girma M, Erickson S, Baker T, Tumas D, Grewal IS, Dixit VM. Activation and accumulation of B cells in TACI-deficient mice.Nat Immunol. 2001 Jul;2(7):638-43.

Anti-Human CD200 PE

货　　号：12-9200-41

产品规格：25 tests

原  产  地：USA

参考价格：1188 （参考价格，以实际价格为准）

优惠价格：

Anti-Human CD200 PE   12-9200-41

 Anti-Human CD200 PE
Also known as: OX-2
Clone: OX104
RUO: For Research Use Only. Not for use in diagnostic procedures.

Host     Mouse
Isotype     IgG1, kappa
Reactivity     Human
Conjugate     PE
Laser     Blue Laser, Green Laser, Yellow-Green Laser
Excite     488 – 561 nm
Reported Applications     Flow Cytometric Analysis

References: Wright GJ, Cherwinski H, Foster-Cuevas M, Brooke G, Puklavec MJ, Bigler M, Song Y, Jenmalm M, Gorman D, McClanahan T, Liu MR, Brown MH, Sedgwick JD, Phillips JH, Barclay AN. Characterization of the CD200 receptor family in mice and humans and their interactions with CD200. J Immunol. 2003 Sep 15;171(6):3034-46.

Barclay AN, Wright GJ, Brooke G, Brown MH. CD200 and membrane protein interactions in the control of myeloid cells. Trends Immunol. 2002 Jun;23(6):285-90. Review.

Wright GJ, Jones M, Puklavec MJ, Brown MH, Barclay AN. The unusual distribution of the neuronal/lymphoid cell surface CD200 (OX2) glycoprotein is conserved in humans. Immunology. 2001 Feb;102(2):173-9. (OX104, FC IHf, PubMed)

Anti-Human CD185 (CXCR5) PE

货　　号：12-9185-41

产品规格：25 tests

原  产  地：USA

参考价格：1548 （参考价格，以实际价格为准）

优惠价格：

Anti-Human CD185 (CXCR5) PE   12-9185-41

Also known as: C-X-C chemokine receptor type 5, BLR1, MDR15
Clone: MU5UBEE
RUO: For Research Use Only. Not for use in diagnostic procedures.
Host     Mouse
Isotype     IgG2b, kappa
Reactivity     Human, Rhesus
Conjugate     PE
Laser     Blue Laser, Green Laser, Yellow-Green Laser
Excite     488 – 561 nm
Reported Applications     Flow Cytometric Analysis

References: Reinhardt RL, Liang HE, Locksley RM. Cytokine-secreting follicular T cells shape the antibody repertoire. Nat Immunol. 2009 Apr;10(4):385-93.

Muller G, Hopken UE, Stein H, Lipp M. Systemic immunoregulatory and pathogenic functions of homeostatic chemokine receptors. J Leukoc Biol. 2002 Jul; 72(1):1-8.

Förster R, Mattis AE, Kremmer E, Wolf E, Brem G, Lipp M. A putative chemokine receptor, BLR1, directs B cell migration to defined lymphoid organs and specific anatomic compartments of the spleen. Cell. 1996 Dec 13;87(6):1037-47.

Barella L, Loetscher M, Tobler A, Baggiolini M, Moser B. Sequence variation of a novel heptahelical leucocyte receptor through alternative transcript formation. Biochem J. 1995 Aug 1;309 ( Pt 3):773-9.

Dobner T, Wolf I, Emrich T, Lipp M. Differentiation-specific expression of a novel G protein-coupled receptor from Burkitt’s lymphoma. Eur J Immunol. 1992 Nov;22(11):2795-9.

Anti-Human CD289 (TLR9) PE

货　　号：12-9099-80

产品规格：25 ug

原  产  地：USA

参考价格：1788 （参考价格，以实际价格为准）

优惠价格：

Anti-Human CD289 (TLR9) PE   12-9099-80

Also known as: TLR-9, toll-like receptor 9
Clone: eB72-1665
RUO: For Research Use Only. Not for use in diagnostic procedures.
Host     Rat
Isotype     IgG2a, kappa
Reactivity     Human
Conjugate     PE
Laser     Blue Laser, Green Laser, Yellow-Green Laser
Excite     488 – 561 nm
Reported Applications     Intracellular Staining Followed by Flow Cytometric Analysis

References: Peduzzi E, Groeper C, et al. 2007. Local activation of the innate immune system in Buruli ulcer lesions. J Invest Dermatol. 127(3):638-45. (eB72-1665, IHC paraffin, PubMed)

Jozsef L, Khreiss T, El Kebir D, Filep JG. Activation of TLR-9 induces IL-8 secretion through peroxynitrite signaling in human neutrophils. J Immunol. 2006 Jan 15;176(2):1195-202. (eB72-1665, FC, PubMed)

Schroeder JT, Bieneman AP, et al. 2005. TLR9- and FcepsilonRI-mediated responses oppose one another in plasmacytoid dendritic cells by down-regulating receptor expression. J Immunol. 175(9):5724-31. (eB72-1665, WB, PubMed)

Dasari P, Nicholson IC, et al. 2005. Expression of toll-like receptors on B lymphocytes. Cell Immunol. 236(1-2):140-5. (eB72-1665, IC flow, PubMed)

Latz E, Schoenemeyer A, Visintin A, Fitzgerald KA, Monks BG, Knetter CF, Lien E, Nilsen NJ, Espevik T, Golenbock DT. 2004. TLR9 signals after translocating from the ER to CpG DNA in the lysosome. Nat Immunol. 5(2):190-8.

Juliane Platz, Christoph Beisswenger, Alexander Dalpke, Rembert Koczulla, Olaf Pinkenburg, Claus Vogelmeier, and Robert Bals. 2004. Microbial DNA Induces a Host Defense Reaction of Human Respiratory Epithelial Cells. J. Immunol. 173: 1219 – 1223.

Leifer CA, Kennedy MN, et al. 2004. TLR9 is localized in the endoplasmic reticulum prior to stimulation. J Immunol. 173(2):1179-83. (Immunofluorescence and IP, PubMed)

Anti-Human CD283 (TLR3) PE

货　　号：12-9039-80

产品规格：25 ug

原  产  地：USA

参考价格：2148 （参考价格，以实际价格为准）

优惠价格：

Anti-Human CD283 (TLR3) PE   12-9039-80

Also known as: TLR-3, toll-like receptor 3
Clone: TLR3.7
RUO: For Research Use Only. Not for use in diagnostic procedures.
Host     Mouse
Isotype     IgG1, kappa
Reactivity     Human
Conjugate     PE
Laser     Blue Laser, Green Laser, Yellow-Green Laser
Emit     575 nm
Excite     488 – 561 nm
Reported Applications     Intracellular Staining Followed by Flow Cytometric Analysis

References: Schreiner B, Voss J, Wischhusen J, Dombrowski Y, Steinle A, Lochmüller H, Dalakas M, Melms A, Wiendl H.. Expression of toll-like receptors by human muscle cells in vitro and in vivo: TLR3 is highly expressed in inflammatory and HIV myopathies, mediates IL-8 release and up-regulation of NKG2D-ligands. FASEB J. 2006 Jan;20(1):118-20. (IHC frozen and WB, PubMed)

Sonali K. Sanghavi and Todd A. Reinhart Increased Expression of TLR3 in Lymph Nodes during Simian Immunodeficiency Virus Infection: Implications for Inflammation and Immunodeficiency. J Immunol. 2005 Oct 15;175(8):5314-23. (TLR3.7, rhesus monkey, IHC (frozen) and intracellular flow cytometry PubMed)

Jorgenson RL, Young SL, Lesmeister MJ, Lyddon TD, Misfeldt ML. Human endometrial epithelial cells cyclically express toll-like receptor 3 (TLR3) and exhibit TLR3-dependent responses to dsRNA. Hum Immunol. 2005 May;66(5):469-82. (IHC paraffin and IHC frozen, PubMed)

Oshiumi H, Matsumoto M, Funami K, Akazawa T, Seya T. 2003. TICAM-1, an adaptor molecule that participates in Toll-like receptor 3-mediated interferon-beta induction. Nat Immunol. 4:161-7

Matsumoto M, Kikkawa S, Kohase M, Miyake K, Seya T. 2002. Establishment of a monoclonal antibody against human Toll-like receptor 3 that blocks double-stranded RNA-mediated signaling. Biochem Biophys Res Commun. 293:1364-9

Alexopoulou L, Holt AC, Medzhitov R, Flavell RA. 2001. Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3. Nature. 413:732-8

Anti-Human CD283 (TLR3) PE

货　　号：12-9039-80

产品规格：25 ug

原  产  地：USA

参考价格：2148 （参考价格，以实际价格为准）

优惠价格：

Anti-Human CD283 (TLR3) PE   12-9039-80

Also known as: TLR-3, toll-like receptor 3
Clone: TLR3.7
RUO: For Research Use Only. Not for use in diagnostic procedures.
Host     Mouse
Isotype     IgG1, kappa
Reactivity     Human
Conjugate     PE
Laser     Blue Laser, Green Laser, Yellow-Green Laser
Emit     575 nm
Excite     488 – 561 nm
Reported Applications     Intracellular Staining Followed by Flow Cytometric Analysis

References: Schreiner B, Voss J, Wischhusen J, Dombrowski Y, Steinle A, Lochmüller H, Dalakas M, Melms A, Wiendl H.. Expression of toll-like receptors by human muscle cells in vitro and in vivo: TLR3 is highly expressed in inflammatory and HIV myopathies, mediates IL-8 release and up-regulation of NKG2D-ligands. FASEB J. 2006 Jan;20(1):118-20. (IHC frozen and WB, PubMed)

Sonali K. Sanghavi and Todd A. Reinhart Increased Expression of TLR3 in Lymph Nodes during Simian Immunodeficiency Virus Infection: Implications for Inflammation and Immunodeficiency. J Immunol. 2005 Oct 15;175(8):5314-23. (TLR3.7, rhesus monkey, IHC (frozen) and intracellular flow cytometry PubMed)

Jorgenson RL, Young SL, Lesmeister MJ, Lyddon TD, Misfeldt ML. Human endometrial epithelial cells cyclically express toll-like receptor 3 (TLR3) and exhibit TLR3-dependent responses to dsRNA. Hum Immunol. 2005 May;66(5):469-82. (IHC paraffin and IHC frozen, PubMed)