VivoTrack 680 NIR Fluorescent Imaging Agent

VivoTrack 680是一种水溶性NIR（近红外）荧光细胞标记剂，可以标记多种细胞类型。 由于细胞迁移对于许多重要的体内生物学功能至关重要，因此这种标记方法有可能为炎症，免疫学和干细胞研究提供有用的工具。 VivoTrack 680可以明亮，均匀地标记细胞，而无需使用苛刻的有机物（例如DMSO或乙醇）或已知会影响细胞功能的化学物质。 标记的细胞保留了出色的生存力和正常的增殖能力，并且在体外分裂细胞中保留了超过7天的明显信号。 可以标记许多不同的细胞类型以用于体内转移或植入，并且通过NIR荧光成像以非侵入性方式将荧光原代巨噬细胞追踪到炎症部位来说明体内效用。

VivoTrack 680 is a water soluble NIR (near infrared) fluorescent cell labeling agent that can label a variety of cell types. As cell migration is critical for many important in vivo biological functions, this labeling approach has the potential to provide a useful tool for research in inflammation, immunology and stem cells.  VivoTrack 680 can label cells brightly and uniformly without requiring harsh organics such as DMSO or ethanol, chemicals known to affect cell function. The labeled cells retain excellent viability and normal proliferative capacity, and significant signal is retained in dividing cells in vitro for more than 7 days. Many different cell types can be labeled for in vivo transfer or implantation, and in vivo utility is illustrated by non-invasively tracking fluorescent primary macrophages to sites of inflammation by NIR fluorescent imaging.