标签归档：murine

Qproteome Murine Albumin Depletion Kit 货号：37591

发表于2022年4月12日由上海金畔生物科技有限公司

Qproteome Murine Albumin Depletion Kit

货　　号：37591

产品规格：

原  产  地：德国

参考价格：4240 （参考价格，以实际价格为准）

优惠价格：

产品详细信息

Qproteome Murine Albumin Depletion Kit

37591

从小鼠和大鼠的血清和血浆样本中去除白蛋白

• 高效去除小鼠和大鼠的白蛋白
• 使用固定的单克隆抗体高特异性去除白蛋白
• 离心柱规格，方便快捷
• 可协助对低丰度蛋白的分析
• 高效的实验流程节约时间

该试剂盒包含去除小鼠和大鼠血清和血浆样本中白蛋白和IgG的离心柱。该试剂盒在QIAcube全自动核酸纯化仪上自动化操作时需要使用Spin Column Adapter Rings。

原理

样本中的白蛋白通过与固定在离心柱的抗体结合而被去除。

操作流程

将稀释的样本上样至树脂离心柱中，然后密封并且进行摇床培养。去除白蛋白的血浆和血清蛋白，可通过离心回收（参见Qproteome Albumin/IgG Depletion Kit procedure）。

应用

Qproteome Murine Albumin Depletion Kit适用于低丰度蛋白质的分析。

产品详细信息

Qproteome Murine Albumin Depletion Kit

37591

从小鼠和大鼠的血清和血浆样本中去除白蛋白

• 高效去除小鼠和大鼠的白蛋白
• 使用固定的单克隆抗体高特异性去除白蛋白
• 离心柱规格，方便快捷
• 可协助对低丰度蛋白的分析
• 高效的实验流程节约时间

该试剂盒包含去除小鼠和大鼠血清和血浆样本中白蛋白和IgG的离心柱。该试剂盒在QIAcube全自动核酸纯化仪上自动化操作时需要使用Spin Column Adapter Rings。

原理

样本中的白蛋白通过与固定在离心柱的抗体结合而被去除。

操作流程

将稀释的样本上样至树脂离心柱中，然后密封并且进行摇床培养。去除白蛋白的血浆和血清蛋白，可通过离心回收（参见Qproteome Albumin/IgG Depletion Kit procedure）。

应用

Qproteome Murine Albumin Depletion Kit适用于低丰度蛋白质的分析。

Murine EGF 货号：315-09

发表于2022年3月19日由上海金畔生物科技有限公司

Murine EGF

货　　号：315-09

产品规格：500ug

原  产  地：USA

参考价格：2340 （参考价格，以实际价格为准）

优惠价格：

产品详细信息

Murine EGF  315-09

别名:

Epidermal Growth Factor, Urogastrone, URG

描述:

EGF is a potent growth factor that stimulates the proliferation of various epidermal and epithelial cells. Additionally, EGF has been shown to inhibit gastric secretion, and to be involved in wound healing. EGF signals through a receptor known as c-erbB, which is a class I tyrosine kinase receptor. This receptor also binds with TGF-α and VGF (vaccinia virus growth factor). Recombinant Murine EGF is a 6.0 kDa globular protein containing 53 amino acid residues, including 3 intramolecular disulfide bonds.

氨基酸序列:

NSYPGCPSSY DGYCLNGGVC MHIESLDSYT CNCVIGYSGD RCQTRDLRWW ELR

来源:

E.coli

纯度:

Greater than 98% by SDS-PAGE gel and HPLC analyses.

生物活性:

The ED₅₀ was determined by a cell proliferation assay using BALB/c 3T3 cells is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 10⁷ units/mg.

产品详细信息

Murine EGF  315-09

别名:

Epidermal Growth Factor, Urogastrone, URG

描述:

EGF is a potent growth factor that stimulates the proliferation of various epidermal and epithelial cells. Additionally, EGF has been shown to inhibit gastric secretion, and to be involved in wound healing. EGF signals through a receptor known as c-erbB, which is a class I tyrosine kinase receptor. This receptor also binds with TGF-α and VGF (vaccinia virus growth factor). Recombinant Murine EGF is a 6.0 kDa globular protein containing 53 amino acid residues, including 3 intramolecular disulfide bonds.

氨基酸序列:

NSYPGCPSSY DGYCLNGGVC MHIESLDSYT CNCVIGYSGD RCQTRDLRWW ELR

来源:

E.coli

纯度:

Greater than 98% by SDS-PAGE gel and HPLC analyses.

生物活性:

The ED₅₀ was determined by a cell proliferation assay using BALB/c 3T3 cells is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 10⁷ units/mg.

Murine GDNF 货号：450-44

发表于2022年3月19日由上海金畔生物科技有限公司

Murine GDNF

货　　号：450-44

产品规格：10ug

原  产  地：USA

参考价格：2340 （参考价格，以实际价格为准）

优惠价格：

产品详细信息

Murine GDNF  450-44

别名:

Glial-Derived Neurotrophic Factor, ATF-1

描述:

GDNF is a disulfide-linked homodimeric neurotrophic factor structurally related to Artemin, Neurturin and Persephin. These proteins belong to the cysteine-knot superfamily of growth factors that assume stable dimeric protein structures. GDNF signals through a multicomponent receptor system, composed of a RET and one of the four GFR α(α1-α4) receptors. GDNF specifically promotes dopamine uptake and survival and morphological differentiation of midbrain neurons. Using Parkinson’s disease mouse model, GDNF has been shown to improve conditions such as bradykinesia, rigidity, and postural instability. The functional murine GDNF ligand is a disulfide-linked homodimer, of two 15.1 kDa polypeptide chains called monomers. Each monomer contains seven conserved cysteine residues, one of which is used for inter-chain disulfide bridging and the others are involved in intramolecular ring formation known as the cysteine knot configuration.

氨基酸序列:

MSPDKQAAAL PRRERNRQAA AASPENSRGK GRRGQRGKNR GCVLTAIHLN VTDLGLGYET KEELIFRYCS GSCESAETMY DKILKNLSRS RRLTSDKVGQ ACCRPVAFDD DLSFLDDNLV YHILRKHSAK RCGCI

来源:

E.coli

纯度:

Greater than 98% by SDS-PAGE gel and HPLC analyses.

生物活性:

The ED₅₀ was determined by the proliferation of rat C6 cells is ≤ 0.2 ng/ml, corresponding to a specific activity of ≥ 5 x 10⁶ units/mg.

产品详细信息

Murine GDNF  450-44

别名:

Glial-Derived Neurotrophic Factor, ATF-1

描述:

GDNF is a disulfide-linked homodimeric neurotrophic factor structurally related to Artemin, Neurturin and Persephin. These proteins belong to the cysteine-knot superfamily of growth factors that assume stable dimeric protein structures. GDNF signals through a multicomponent receptor system, composed of a RET and one of the four GFR α(α1-α4) receptors. GDNF specifically promotes dopamine uptake and survival and morphological differentiation of midbrain neurons. Using Parkinson’s disease mouse model, GDNF has been shown to improve conditions such as bradykinesia, rigidity, and postural instability. The functional murine GDNF ligand is a disulfide-linked homodimer, of two 15.1 kDa polypeptide chains called monomers. Each monomer contains seven conserved cysteine residues, one of which is used for inter-chain disulfide bridging and the others are involved in intramolecular ring formation known as the cysteine knot configuration.

氨基酸序列:

MSPDKQAAAL PRRERNRQAA AASPENSRGK GRRGQRGKNR GCVLTAIHLN VTDLGLGYET KEELIFRYCS GSCESAETMY DKILKNLSRS RRLTSDKVGQ ACCRPVAFDD DLSFLDDNLV YHILRKHSAK RCGCI

来源:

E.coli

纯度:

Greater than 98% by SDS-PAGE gel and HPLC analyses.

生物活性:

The ED₅₀ was determined by the proliferation of rat C6 cells is ≤ 0.2 ng/ml, corresponding to a specific activity of ≥ 5 x 10⁶ units/mg.

Murine VEGF 货号：450-32

发表于2022年3月19日由上海金畔生物科技有限公司

Murine VEGF

货　　号：450-32

产品规格：10ug

原  产  地：USA

参考价格：2340 （参考价格，以实际价格为准）

优惠价格：

产品详细信息

Murine VEGF  450-32

别名:

Vascular Endothelial Growth Factor, VPF, Folliculostellate cell-derived growth factor, Glioma-derived endothelial cell mitogen, VEGF₁₆₅

描述:

VEGF is a potent growth and angiogenic cytokine. It stimulates proliferation and survival of endothelial cells, and promotes angiogenesis and vascular permeability. Expressed in vascularized tissues, VEGF plays a prominent role in normal and pathological angiogenesis. Substantial evidence implicates VEGF in the induction of tumor metastasis and intra-ocular neovascular syndromes. VEGF signals through the three receptors; fms-like tyrosine kinase (flt-1), KDR gene product (the murine homolog of KDR is the flk-1 gene product) and the flt4 gene product. Recombinant murine VEGF is a 39.0 kDa disulfide-linked homodimeric protein consisting of two 165 amino acid polypeptide chains.

氨基酸序列:

MAPTTEGEQK SHEVIKFMDV YQRSYCRPIE TLVDIFQEYP DEIEYIFKPS CVPLMRCAGC CNDEALECVP TSESNITMQI MRIKPHQSQH IGEMSFLQHS RCECRPKKDR TKPEKHCEPC SERRKHLFVQ DPQTCKCSCK NTDSRCKARQ LELNERTCRC DKPRR

来源:

E.coli

纯度:

Greater than 98% by SDS-PAGE gel and HPLC analyses.

生物活性:

Determined by the dose-dependent stimulation of the proliferation of human umbilical vein endothelial cells (HUVEC) using a concentration range of 1.0-5.0 ng/ml.

产品详细信息

Murine VEGF  450-32

别名:

Vascular Endothelial Growth Factor, VPF, Folliculostellate cell-derived growth factor, Glioma-derived endothelial cell mitogen, VEGF₁₆₅

描述:

VEGF is a potent growth and angiogenic cytokine. It stimulates proliferation and survival of endothelial cells, and promotes angiogenesis and vascular permeability. Expressed in vascularized tissues, VEGF plays a prominent role in normal and pathological angiogenesis. Substantial evidence implicates VEGF in the induction of tumor metastasis and intra-ocular neovascular syndromes. VEGF signals through the three receptors; fms-like tyrosine kinase (flt-1), KDR gene product (the murine homolog of KDR is the flk-1 gene product) and the flt4 gene product. Recombinant murine VEGF is a 39.0 kDa disulfide-linked homodimeric protein consisting of two 165 amino acid polypeptide chains.

氨基酸序列:

MAPTTEGEQK SHEVIKFMDV YQRSYCRPIE TLVDIFQEYP DEIEYIFKPS CVPLMRCAGC CNDEALECVP TSESNITMQI MRIKPHQSQH IGEMSFLQHS RCECRPKKDR TKPEKHCEPC SERRKHLFVQ DPQTCKCSCK NTDSRCKARQ LELNERTCRC DKPRR

来源:

E.coli

纯度:

Greater than 98% by SDS-PAGE gel and HPLC analyses.

生物活性:

Determined by the dose-dependent stimulation of the proliferation of human umbilical vein endothelial cells (HUVEC) using a concentration range of 1.0-5.0 ng/ml.

Murine GM-CSF 货号：315-03

发表于2022年3月18日由上海金畔生物科技有限公司

Murine GM-CSF

货　　号：315-03

产品规格：20ug

原  产  地：USA

参考价格：2340 （参考价格，以实际价格为准）

优惠价格：

产品详细信息

Murine GM-CSF  315-03

别名:

Granulocyte/Macrophage Colony-Stimulating Factor, CSF-2, MGI-1GM, pluripoietin-alpha

描述:

GM-CSF is a hematopoietic growth factor that stimulates the development of neutrophils and macrophages and promotes the proliferation and development of early erythroid megakaryocytic and eosinophilic progenitor cells. It is produced in endothelial cells, monocytes, fibroblasts and T-lymphocytes. GM-CSF inhibits neutrophil migration and enhances the functional activity of the mature end-cells. The human and murine molecules are species-specific and exhibit no cross-species reactivity. Recombinant murine GM-CSF is a 14.2 kDa globular protein consisting of 125 amino acid residues.

氨基酸序列:

MAPTRSPITV TRPWKHVEAI KEALNLLDDM PVTLNEEVEV VSNEFSFKKL TCVQTRLKIF EQGLRGNFTK LKGALNMTAS YYQTYCPPTP ETDCETQVTT YADFIDSLKT FLTDIPFECK KPVQK

来源:

E.coli

纯度:

Greater than 98% by SDS-PAGE gel and HPLC analyses.

生物活性:

The ED₅₀ as determined by the dose-dependent stimulation of the proliferation of murine FDC-P1 cells is ≤ 0.05 ng/ml, corresponding to a specific activity of ≥ 2 x 10⁷ units/mg.

产品详细信息

Murine GM-CSF  315-03

别名:

Granulocyte/Macrophage Colony-Stimulating Factor, CSF-2, MGI-1GM, pluripoietin-alpha

描述:

GM-CSF is a hematopoietic growth factor that stimulates the development of neutrophils and macrophages and promotes the proliferation and development of early erythroid megakaryocytic and eosinophilic progenitor cells. It is produced in endothelial cells, monocytes, fibroblasts and T-lymphocytes. GM-CSF inhibits neutrophil migration and enhances the functional activity of the mature end-cells. The human and murine molecules are species-specific and exhibit no cross-species reactivity. Recombinant murine GM-CSF is a 14.2 kDa globular protein consisting of 125 amino acid residues.

氨基酸序列:

MAPTRSPITV TRPWKHVEAI KEALNLLDDM PVTLNEEVEV VSNEFSFKKL TCVQTRLKIF EQGLRGNFTK LKGALNMTAS YYQTYCPPTP ETDCETQVTT YADFIDSLKT FLTDIPFECK KPVQK

来源:

E.coli

纯度:

Greater than 98% by SDS-PAGE gel and HPLC analyses.

生物活性:

The ED₅₀ as determined by the dose-dependent stimulation of the proliferation of murine FDC-P1 cells is ≤ 0.05 ng/ml, corresponding to a specific activity of ≥ 2 x 10⁷ units/mg.

Murine SCF 货号：250-03

发表于2022年3月18日由上海金畔生物科技有限公司

Murine SCF

货　　号：250-03

产品规格：10ug

原  产  地：USA

参考价格：2340 （参考价格，以实际价格为准）

优惠价格：

产品详细信息

Murine SCF  250-03

别名:

Stem Cell Factor, c-Kit Ligand, Mast Cell Growth Factor (MGF), Steel Factor

描述:

SCF is a hematopoietic growth factor that exerts its activity by signaling through the c-Kit receptor. SCF and c-Kit are essential for the survival, proliferation and differentiation of hematopoietic cells committed to the melanocyte and germ cell lineages. Human SCF manifests low activity on murine cells, while murine and rat SCF are fully active on human cells. Recombinant murine SCF is an 18.3 kDa polypeptide containing 164 amino acid residues, which corresponds to the sequence of the secreted soluble form of SCF.

氨基酸序列:

MKEICGNPVT DNVKDITKLV ANLPNDYMIT LNYVAGMDVL PSHCWLRDMV IQLSLSLTTL LDKFSNISEG LSNYSIIDKL GKIVDDLVLC MEENAPKNIK ESPKRPETRS FTPEEFFSIF NRSIDAFKDF MVASDTSDCV LSSTLGPEKD SRVSVTKPFM LPPVA

来源:

E.coli

纯度:

Greater than 98% by SDS-PAGE gel and HPLC analyses.

生物活性:

The ED₅₀ as determined by the dose-dependent stimulation of the proliferation of the human TF-1 cells is < 10 ng/ml, corresponding to a specific activity of > 1 x 10⁵ units/mg.

产品详细信息

Murine SCF  250-03

别名:

Stem Cell Factor, c-Kit Ligand, Mast Cell Growth Factor (MGF), Steel Factor

描述:

SCF is a hematopoietic growth factor that exerts its activity by signaling through the c-Kit receptor. SCF and c-Kit are essential for the survival, proliferation and differentiation of hematopoietic cells committed to the melanocyte and germ cell lineages. Human SCF manifests low activity on murine cells, while murine and rat SCF are fully active on human cells. Recombinant murine SCF is an 18.3 kDa polypeptide containing 164 amino acid residues, which corresponds to the sequence of the secreted soluble form of SCF.

氨基酸序列:

MKEICGNPVT DNVKDITKLV ANLPNDYMIT LNYVAGMDVL PSHCWLRDMV IQLSLSLTTL LDKFSNISEG LSNYSIIDKL GKIVDDLVLC MEENAPKNIK ESPKRPETRS FTPEEFFSIF NRSIDAFKDF MVASDTSDCV LSSTLGPEKD SRVSVTKPFM LPPVA

来源:

E.coli

纯度:

Greater than 98% by SDS-PAGE gel and HPLC analyses.

生物活性:

The ED₅₀ as determined by the dose-dependent stimulation of the proliferation of the human TF-1 cells is < 10 ng/ml, corresponding to a specific activity of > 1 x 10⁵ units/mg.

Murine NOGGIN 货号：250-38

发表于2022年3月18日由上海金畔生物科技有限公司

Murine NOGGIN

货　　号：250-38

产品规格：5ug

原  产  地：USA

参考价格：960 （参考价格，以实际价格为准）

优惠价格：

产品详细信息

Murine NOGGIN  250-38

描述:

Noggin belongs to a group of diffusible proteins which bind to ligands of the TGF-β family and regulate their activity by inhibiting their access to signaling receptors. The interplay between TGF-β ligands and their natural antagonists has major biological significance during development processes, in which cellular response can vary considerably depending upon the local concentration of the signaling molecule. Noggin was originally identified as a BMP-4 antagonist whose action is critical for proper formation of the head and other dorsal structures. Consequently, Noggin has been shown to modulate the activities of other BMPs including BMP-2,-7,-13, and -14. Targeted deletion of Noggin in mice results in prenatal death and recessive phenotype displaying a severely malformed skeletal system. Conversely, transgenic mice over-expressing Noggin in mature osteoblasts display impaired osteoblastic differentiation, reduced bone formation, and severe osteoporosis. Recombinant murine Noggin is a 46.4 kDa disulfide-linked homodimer consisting of two 206 amino acid polypeptide chains.

氨基酸序列:

MQHYLHIRPA PSDNLPLVDL IEHPDPIFDP KEKDLNETLL RSLLGGHYDP GFMATSPPED RPGGGGGPAG GAEDLAELDQ LLRQRPSGAM PSEIKGLEFS EGLAQGKKQR LSKKLRRKLQ MWLWSQTFCP VLYAWNDLGS RFWPRYVKVG SCFSKRSCSV PEGMVCKPSK SVHLTVLRWR CQRRGGQRCG WIPIQYPIIS ECKCSC

来源:

E.coli

纯度:

Greater than 95% by SDS-PAGE gel and HPLC analyses.

产品详细信息

Murine NOGGIN  250-38

描述:

Noggin belongs to a group of diffusible proteins which bind to ligands of the TGF-β family and regulate their activity by inhibiting their access to signaling receptors. The interplay between TGF-β ligands and their natural antagonists has major biological significance during development processes, in which cellular response can vary considerably depending upon the local concentration of the signaling molecule. Noggin was originally identified as a BMP-4 antagonist whose action is critical for proper formation of the head and other dorsal structures. Consequently, Noggin has been shown to modulate the activities of other BMPs including BMP-2,-7,-13, and -14. Targeted deletion of Noggin in mice results in prenatal death and recessive phenotype displaying a severely malformed skeletal system. Conversely, transgenic mice over-expressing Noggin in mature osteoblasts display impaired osteoblastic differentiation, reduced bone formation, and severe osteoporosis. Recombinant murine Noggin is a 46.4 kDa disulfide-linked homodimer consisting of two 206 amino acid polypeptide chains.

氨基酸序列:

MQHYLHIRPA PSDNLPLVDL IEHPDPIFDP KEKDLNETLL RSLLGGHYDP GFMATSPPED RPGGGGGPAG GAEDLAELDQ LLRQRPSGAM PSEIKGLEFS EGLAQGKKQR LSKKLRRKLQ MWLWSQTFCP VLYAWNDLGS RFWPRYVKVG SCFSKRSCSV PEGMVCKPSK SVHLTVLRWR CQRRGGQRCG WIPIQYPIIS ECKCSC

来源:

E.coli

纯度:

Greater than 95% by SDS-PAGE gel and HPLC analyses.

Murine FGF-basic小鼠BFGF 货号：450-33

发表于2022年3月18日由上海金畔生物科技有限公司

Murine FGF-basic小鼠BFGF

货　　号：450-33

产品规格：10ug

原  产  地：USA

参考价格：960 （参考价格，以实际价格为准）

优惠价格：

产品详细信息

Murine FGF-basic小鼠BFGF 450-33

别名:

Fibroblast Growth Factor-basic, FGF-2, HBGF-2, Prostatropin

描述:

FGF-basic is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-basic is a non-glycosylated heparin binding growth factor that is expressed in the brain, pituitary, kidney, retina, bone, testis, adrenal gland, liver, monocytes, epithelial cells and endothelial cells. FGF-basic signals through FGFR 1b, 1c, 2c, 3c and 4. Recombinant Murine FGF-basic is a 16.3 kDa protein consisting of 145 amino acid residues.

氨基酸序列:

PALPEDGGAA FPPGHFKDPK RLYCKNGGFF LRIHPDGRVD GVREKSDPHV KLQLQAEERG VVSIKGVCAN RYLAMKEDGR LLASKCVTEE CFFFERLESN NYNTYRSRKY SSWYVALKRT GQYKLGSKTG PGQKAILFLP MSAKS

来源:

E.coli

纯度:

Greater than 95% by SDS-PAGE gel and HPLC analyses.

生物活性:

Assay #1: The ED₅₀ as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF receptors is ≤ 0.1 ng/ml corresponding to a specific activity of ≥ 1 x 10⁷ units/mg.

Assay #2: The ED₅₀ was determined by a cell proliferation assay using balb/c 3T3 cells is ≤ 1.0 ng/ml, corresponding to a specific activity of ≥ 1 x 10⁶ units/mg.

产品详细信息

Murine FGF-basic小鼠BFGF 450-33

别名:

Fibroblast Growth Factor-basic, FGF-2, HBGF-2, Prostatropin

描述:

FGF-basic is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-basic is a non-glycosylated heparin binding growth factor that is expressed in the brain, pituitary, kidney, retina, bone, testis, adrenal gland, liver, monocytes, epithelial cells and endothelial cells. FGF-basic signals through FGFR 1b, 1c, 2c, 3c and 4. Recombinant Murine FGF-basic is a 16.3 kDa protein consisting of 145 amino acid residues.

氨基酸序列:

PALPEDGGAA FPPGHFKDPK RLYCKNGGFF LRIHPDGRVD GVREKSDPHV KLQLQAEERG VVSIKGVCAN RYLAMKEDGR LLASKCVTEE CFFFERLESN NYNTYRSRKY SSWYVALKRT GQYKLGSKTG PGQKAILFLP MSAKS

来源:

E.coli

纯度:

Greater than 95% by SDS-PAGE gel and HPLC analyses.

生物活性:

Assay #1: The ED₅₀ as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF receptors is ≤ 0.1 ng/ml corresponding to a specific activity of ≥ 1 x 10⁷ units/mg.

Assay #2: The ED₅₀ was determined by a cell proliferation assay using balb/c 3T3 cells is ≤ 1.0 ng/ml, corresponding to a specific activity of ≥ 1 x 10⁶ units/mg.

Murine TNF-alpha小鼠TNFα 货号：315-01A

发表于2022年3月18日由上海金畔生物科技有限公司

Murine TNF-alpha小鼠TNFα

货　　号：315-01A

产品规格：5ug

原  产  地：USA

参考价格：960 （参考价格，以实际价格为准）

优惠价格：

产品详细信息

Murine TNF-alpha小鼠TNFα 315-01A

别名:

Tumor Necrosis Factor, TNFSF2, Cachectin, Differentiation-inducing factor (DIF), Necrosin, Cytotoxin

描述:

TNF-α is a pleiotropic pro-inflammatory cytokine secreted by various cells including adipocytes, activated monocytes, macrophages, B cells, T cells and fibroblasts. It belongs to the TNF family of ligands and signals through two receptors, TNFR1 and TNFR2. TNF-α is cytotoxic to a wide variety of tumor cells and is an essential factor in mediating the immune response against bacterial infections. TNF-α also plays a role in the induction of septic shock, auto immune diseases, rheumatoid arthritis, inflammation, and diabetes. Recombinant murine TNF-α is a soluble 156 amino acid protein (17.3 kDa) which corresponds to C-terminal extracellular domain of the full length transmembrane protein.

氨基酸序列:

MLRSSSQNSS DKPVAHVVAN HQVEEQLEWL SQRANALLAN GMDLKDNQLV VPADGLYLVY SQVLFKGQGC PDYVLLTHTV SRFAISYQEK VNLLSAVKSP CPKDTPEGAE LKPWYEPIYL GGVFQLEKGD QLSAEVNLPK YLDFAESGQV YFGVIAL

来源:

E.coli

纯度:

Greater than 98% by SDS-PAGE gel and HPLC analyses.

生物活性:

The ED₅₀ as determined by the cytolysis of murine L929 cells in the presence of actinomycin D is ≤ 0.1 ng/ml, corresponding to a specific activity of  ≥ 1 x 10⁷ units/mg.

产品详细信息

Murine TNF-alpha小鼠TNFα 315-01A

别名:

Tumor Necrosis Factor, TNFSF2, Cachectin, Differentiation-inducing factor (DIF), Necrosin, Cytotoxin

描述:

TNF-α is a pleiotropic pro-inflammatory cytokine secreted by various cells including adipocytes, activated monocytes, macrophages, B cells, T cells and fibroblasts. It belongs to the TNF family of ligands and signals through two receptors, TNFR1 and TNFR2. TNF-α is cytotoxic to a wide variety of tumor cells and is an essential factor in mediating the immune response against bacterial infections. TNF-α also plays a role in the induction of septic shock, auto immune diseases, rheumatoid arthritis, inflammation, and diabetes. Recombinant murine TNF-α is a soluble 156 amino acid protein (17.3 kDa) which corresponds to C-terminal extracellular domain of the full length transmembrane protein.

氨基酸序列:

MLRSSSQNSS DKPVAHVVAN HQVEEQLEWL SQRANALLAN GMDLKDNQLV VPADGLYLVY SQVLFKGQGC PDYVLLTHTV SRFAISYQEK VNLLSAVKSP CPKDTPEGAE LKPWYEPIYL GGVFQLEKGD QLSAEVNLPK YLDFAESGQV YFGVIAL

来源:

E.coli

纯度:

Greater than 98% by SDS-PAGE gel and HPLC analyses.

生物活性:

The ED₅₀ as determined by the cytolysis of murine L929 cells in the presence of actinomycin D is ≤ 0.1 ng/ml, corresponding to a specific activity of  ≥ 1 x 10⁷ units/mg.

Murine IL-6小鼠白介素6 货号：216-16

发表于2022年3月18日由上海金畔生物科技有限公司

Murine IL-6小鼠白介素6

货　　号：216-16

产品规格：10ug

原  产  地：USA

参考价格：2340 （参考价格，以实际价格为准）

优惠价格：

产品详细信息

Murine IL-6小鼠白介素6  216-16

别名:

26 kDa protein, IFN-b2, B cell differentiation factor (BCDF), BSF-2, HPGF, HSF, MGI-2

描述:

IL-6 is a pleiotropic cytokine that plays an important role in host defense by regulating immune and inflammatory responses. Produced by T cells, monocytes, fibroblasts, endothelial cells and keratinocytes, IL-6 has diverse biological functions. It stimulates B-cell differentiation and antibody production, synergizes with IL-3 in megakaryocyte development and platelet production, induces expression of hepatic acute-phase proteins, and regulates bone metabolism. IL-6 signals through the IL-6 receptor system that consists of two chains, IL-6R α and gp130. Murine IL-6 is inactive on human cells, while both human and murine are equally active on murine cells. Recombinant murine IL-6 is a 21.7 kDa protein containing 188 amino acid residues.

氨基酸序列:

MFPTSQVRRG DFTEDTTPNR PVYTTSQVGG LITHVLWEIV EMRKELCNGN SDCMNNDDAL AENNLKLPEI QRNDGCYQTG YNQEICLLKI SSGLLEYHSY LEYMKNNLKD NKKDKARVLQ RDTETLIHIF NQEVKDLHKI VLPTPISNAL LTDKLESQKE WLRTKTIQFI LKSLEEFLKV TLRSTRQT

来源:

E.coli

纯度:

Greater than 98% by SDS-PAGE gel and HPLC analyses.

生物活性:

The ED₅₀ as determined by the dose-dependent stimulation of the proliferation of IL-6-dependent murine 7TD1 cells is ≤ 0.02 ng/ml, corresponding to a specific activity of ≥ 5 x 10⁷ units/mg.

产品详细信息

Murine IL-6小鼠白介素6  216-16

别名:

26 kDa protein, IFN-b2, B cell differentiation factor (BCDF), BSF-2, HPGF, HSF, MGI-2

描述:

IL-6 is a pleiotropic cytokine that plays an important role in host defense by regulating immune and inflammatory responses. Produced by T cells, monocytes, fibroblasts, endothelial cells and keratinocytes, IL-6 has diverse biological functions. It stimulates B-cell differentiation and antibody production, synergizes with IL-3 in megakaryocyte development and platelet production, induces expression of hepatic acute-phase proteins, and regulates bone metabolism. IL-6 signals through the IL-6 receptor system that consists of two chains, IL-6R α and gp130. Murine IL-6 is inactive on human cells, while both human and murine are equally active on murine cells. Recombinant murine IL-6 is a 21.7 kDa protein containing 188 amino acid residues.

氨基酸序列:

MFPTSQVRRG DFTEDTTPNR PVYTTSQVGG LITHVLWEIV EMRKELCNGN SDCMNNDDAL AENNLKLPEI QRNDGCYQTG YNQEICLLKI SSGLLEYHSY LEYMKNNLKD NKKDKARVLQ RDTETLIHIF NQEVKDLHKI VLPTPISNAL LTDKLESQKE WLRTKTIQFI LKSLEEFLKV TLRSTRQT

来源:

E.coli

纯度:

Greater than 98% by SDS-PAGE gel and HPLC analyses.

生物活性:

The ED₅₀ as determined by the dose-dependent stimulation of the proliferation of IL-6-dependent murine 7TD1 cells is ≤ 0.02 ng/ml, corresponding to a specific activity of ≥ 5 x 10⁷ units/mg.